Eoulsan is a command line workflow engine for Next Generation Sequencing data analysis. It could be run either in standalone mode or in distributed mode 
using the Hadoop framework. Eoulsan allows users to easily set up a cloud computing cluster and automate the analysis of several samples at once using various software solutions available. Our tests with Amazon Web Services demonstrated that the computation cost is linear with the number of instances booked as is the running time with the increasing amounts of data. Availability and implementation: Eoulsan is implemented in Java, supported on Linux systems and distributed under the LGPL License at: http://transcriptome.ens.fr/eoulsan/. Currently Eoulsan runs only under Linux (due to mappers binaries dependencies). However Eoulsan core is compatible with all *nix where Java is available.
Reference:
Jourdren L, Bernard M, Dillies MA, Le Crom S. Eoulsan: a cloud computing-based framework facilitating high throughput sequencing analyses. Bioinformatics. 2012 Jun 1;28(11):1542-3. Epub 2012 Apr 5. PubMed PMID: 22492314.
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